To overcome the common bottlenecks where traditional multi-physical field modulations (force, thermal, optical, and electrical) 
are restricted to global effects and fail to balance localized patterning with high efficiency, a high-throughput experimental 
paradigm is introduced in this talk. By leveraging localized thermal-oxygen coupling, precise spatial modulation of 
superconductivity is achieved, facilitating the development of novel high-temperature superconducting (HTS) quantum devices
based on phase transitions. Initially, simulation studies spanning both macroscopic and microscopic dimensions are conducted
to elucidate the interaction laws between laser parameters and HTS materials, thereby guiding the fabrication of high-throughput
micro-regional physical property matrices on the thin films. Subsequently, integrated data analysis is employed to deeply reveal
the intrinsic correlation between localized thermal-oxygen coupling and superconducting order parameters. Building upon these 
insights, novel sensors based on superconducting phase transitions are innovatively developed, establishing a comprehensive R&D
pathway spanning from “physical mechanisms” and “process criteria” to "data patterns” and “device architecture”. 
This research not only establishes a new paradigm for the spatial heterogeneous design of superconducting properties but
also lays a solid technological and theoretical foundation for the integrated development of novel phase-transition-based 
superconducting quantum detectors and functional devices.